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Filling and Distributing of Cell Culture Media - Case study02-03-2021

Cell culture technology has advanced significantly over the last few decades and is now generally considered a reliable, robust and relatively mature technology. A range of biotherapeutics are currently synthesized using cell culture methods in large scale manufacturing facilities.


Performance parameters such as cell growth, viability, metabolites, titer, cell cycle and apoptosis levels should be monitored throughout cell culture. The quality of samples is essential to for the subsequent cell analysis applications. 


The challenges of cell culture media transfer


Cell culture media is a key component of upstream bioprocessing needed to encourage the growth and survival of cells. The ingredients in cell culture media provide a rich nurturing environment for the cells biopharmaceutical manufacturers wish to propagate. This is vital to achieving a viable cell density and, ultimately, the desired product titre. However, its filling and distributing can be a challenge for biopharmaceutical operators.


The role of Longerpump


As such, media and buffer preparation require flexibility of scale without the risk of cross-contamination. And maintaining quality and protecting product integrity during fluid transfer is vital. Longer delivers low-shear and low-pressure pumping specifically for cell culture process.


Longer peristaltic pumps and tubing offer exceptional flow control and process stability to suit different cell culture process needs.


Additionally, Longer pumps also have high filling accuracy and efficiency and protects your valuable product and minimizes risk with minimal operator intervention. And fewer processes also mean quicker upskilling for operators.


Case study

An automatic Media Plate Filler developed for biotechnology laboratory through using Longer peristaltic pumping system, the Media Plate Filler is capable of filling batches of up to 30 SBS format plates with various media. The silicone tubing will be replaced during routine maintenance. 


By working together with the customer, we are able to simplify their product process, reduce the time to process, and reduce the overall cost of the process step.


Longerpump as a provider of fluid transport solutions, has a complete peristaltic pump product line and rich experience in the pharmaceutical industry. Throughout upstream and downstream, we provide accuracy, reliability and purity for all your fluid handling needs. Longer would welcome the opportunity to work together to optimize your bioprocess.




Starting in 1997, Longer is a wholly owned subsidiary of the Halma Group, and is affiliated to Medical Sector. Our product lines, including peristaltic pumps, laboratorial syringe pumps, industrial syringe pumps, micro-gear pumps, dispensing and filling systems, OEM pumps, and more, are sold through company-owned customer channel outlets and a strong network of international dealers. Longerpump responds with excellence to customer needs, and offers application expertise and technical support. For more info: www.longerpump.com

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